Jothydev's Diabetes & Research Center
JDC Junction, Mudavanmugal,
Trivandrum, Kerala, India 695032
tel +91 471 2356200
fax +91 471 2356666
cell +91 984 6040055
www.jothydev.net jothydev@vsnl.com

Jothydev Kesavadev, MD
Research Diabetologist based in Kerala, South India.
Several National and International presentations and publications to his credit.
First speaker from Kerala at American Diabetes Association.
First invited speaker at International Diabetes Federation from Kerala.
 

Present Positions:
    • CEO and Director: Jothydev's Diabetes and Research Center, Trivandrum
• Chairman: Diabscreen Kerala, P.Kesavadev Trust
• Managing Director: Living Longer Life Care (Private Limited)
 

Previously:
    • Director, Indian Institute of Diabetes- 2002
• Asst.Professor of Medicine: Government Medical College, Trivandrum- 2000
• Lecturer in Internal Medicine: Government Medical College, Trivandrum- 1996
 

Education:
    • Endocrinology research fellow at Mayo Clinic, MN, USA- 2003
• MD, Medical College, Trivandrum, Kerala, India- 1996
• MBBS, Medical College, Trivandrum, Kerala, India- 1989
 

Major areas of Research:

    • CGM, Insulin Pumps, Telemedicine
 

Memberships in Professional Associations:

    • American Diabetes Association.
• American Geriatrics Society.
• RSSDI (Research Society for the study of diabetes in India)
• Association of Physicians India (API)
• Indian Medical Association.
• Geriatric Society of India.
• Indian Medical Association, AMS.
• Diabscreen Kerala, doctor's forum.
 

Select Original Research/ Publications/Presentations:
  • "Use of Insulin Pumps in India: Suggested Guidelines based on Experience and Cultural Differences" Kesavadev.J, Das.AK, Joshi.SR, Jothydev.S, Viswanathan.M (accepted for publication, DTT 2010)
  • "Reduction of glycosylated hemoglobin following 6 months of continuous subcutaneous insulin infusion in an Indian population with type 2 diabetes" Kesavadev J, Balakrishnan S, Ahammed S, Jothydev S, Diabetes Technologies and Therapeutics, 2009;11(8):517-521.
• Newer Insulin and Insulin pumps, The Journal of the Association of Physicians of India (Tamil
Nadu Chapter)(TAPIJ), Vol:2, Issue:2, May-Aug 2010: 5-11
• "A Clinician's Perspective on Liraglutide in Clinical Practice", N.Tandon, M.John,
SK Sharma, Jothydev Kesavadev, B.Ganapathy; Supplement to Journal of Association of Physicians India (JAPI), Vol.58, June 2010: 29-30
• Use of Acarbose in graded doses in T2 diabetes subjects to achieve postprandial sugars below 140mg/dl and A1c below 6% with a tele medicine based titration program, Indian Medical Gazette, Nov 2008.
• Gatifloxacin induced abnormalities in glucose homeostasis in a patient on Glimepiride,
Journal of Association of Physicians of India (JAPI), Dec 2006
• Diabetes in old age: an emerging epidemic, Journal of Association of Physicians of India (JAPI),
Nov 2003
• Diabetes in the older patient" chapter in text book on "Primer on Geriatric Care" pg 177,
C.Blaum MD, Jothydev, MD. Oct 2002.
• "Geriatric Principles" chapter in text book on "Primer on Geriatric Care" pg 19, D.ERosenblatt
MD, Jothydev, MD. Oct 2002.
    • American Diabetes Association, Orlando, USA, 2010
      o Telefollow up and SMBG Via "DTMS"- A Cost Effective Tool for A1c Lowering – 2083-PO
o High Prevalence of Elevated Transaminases among T2DM in S.India – 2340-PO
    • American Diabetes Association, New Orleans, USA, June 2009 (speaker)
      o Role of CGM in modifying Diet and Lifestyles in Diabetes subjects – 268-OR.
o Requirement of high dosage of insulin in previous users of Glibenclamide with uncontrolled diabetes – 2079-PO.
    • American Diabetes Association, San Francisco, USA, June 2008
      o Experiences with Insulin Pump in 52 Patients with Type 2 Diabetes in India- 2021-PO
o Insulin Aspart Induced Lipoatrophy in a Patient on Insulin Pump- 2093- PO
o High Prevalence of Dyslipidemia and Hypertension Detected in a Screening Program for Diabetes in a Rural population of a Southern State in India, Kerala (DIABSCREEN KERALA-04) – 2424-PO
o A Study on the Effects of Acarbose in Reducing Post-Prandial Blood Glucose and Achieving HbA1c – 438-P
o Reasons for Failure in Achieving Glycemic Targets in a Subset of Indian Patients with Type 2 Diabetes Mellitus in a Telemedicine Based Follow Up Program.
    • American Diabetes Association, Chicago, June 2007
      o Achieving Desirable Glycemic Targets without the risks of Hypoglycemia using a Tele titration program -0421-P
o Dramatic Response of Painful Peripheral Neuropathy with Insulin Pump in Type 2
Diabetes -2097-PO
    • World Diabetes Congress, International Diabetes Federation, Montreal, Canada 2009
      o Good Nutrition: Avoidance of excess weight with Pumps- Symposium, (an invited Speaker)
o Low compliance of Statins in Kerala Rural Population (Diabscreen 14)
o Successful outcome of a multidisciplinary team over an individual approach in imparting diabetes education.
    • Advanced Technologies and Treatment for Diabetes, Basel, Switzerland, 2010-"Significant Alleviation of Neuropathic Pain with Insulin Pumps (CSII) in T2DM subjects previously on MDI", Abstract [57]
      o Reasons for non compliance to Diabetes Tele Medicine Based Follow up Program in Type 2 Diabetes.
o Insulin Pump in 56 Type 2 diabetes subjects: Improvement of sexual satisfaction and neuropathic symptoms.
    • Advanced Technologies and Treatment for Diabetes, Greece, 2009
 

Research Activities:
  As Principal Investigator for several research studies, a few are given below –
    • Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin in Patients with type 2 Diabetes Mellitus and Inadequate Glycemic Control on Mono- or Dual Combination Oral Antihyperglycemic Therapy : Ongoing study
    • A trial investigating the efficacy and safety of NN1250 compared to insulin detemir in subjects with type 1 diabetes mellitus in a basal/bolus treatment regimen (NN1250-3585): Ongoing study
    • A 26 weeks randomized, multinational, open-labelled, two armed, parallel group, treat-to-target, once daily treatment trial with insulin detemir versus insulin glargine both in combination with metformin in subjects with type 2 diabetes.(NN304-1768) : Ongoing study
    • Use of telemedicine based self monitoring of blood glucose program to achieve target HbA1c value without serious symptomatic hypoglycaemia along with economic benefit in 1000 patients with type 2 diabetes mellitus. : Retrospective study (IIS)
    • Principal Investigator for Inhaled human insulin with the AERx iDMS as prandial monotherapy compared to combination therapy with metformin and glimeperide in type 2 diabetes: an 18 week, open-label, multicentre, randomized, parallel group trial with an 8 week extension to investigate efficacy and safety. (Protocol ID: NN1998-1787) : Site Closure – October 2008
    • PERSISTence on glimepiride-metformin fixed combination in everyday practice in Asia type 2 diabetes patients: Study Completed
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